ORIGINAL ARTICLE

Evaluation of thrombolytic, membrane stabilizing, and antioxidant activities of methanolic extract of Tabernaemontana recurva Roxb.

Sujan Banik

Sujan Banik
. Email: pharmasujan@yahoo.com
Online First: April 15, 2017 | Cite this Article
Banik, S. 2017. Evaluation of thrombolytic, membrane stabilizing, and antioxidant activities of methanolic extract of Tabernaemontana recurva Roxb.. Discovery Phytomedicine 4(2): 17-20. DOI:10.15562/phytomedicine.2017.40


This study was undertaken to elucidate preliminary phytochemical and pharmacological investigations like thrombolytic, membrane stabilizing activity, and antioxidant property on methanolic extract of Tabernaemontana recurva. Thrombolytic test was done by using streptokinase enzyme as the standard, whereas acetyl salicylic acid used as a standard for determination of membrane stabilizing potential and antioxidant property was tabulated as gallic acid equivalent (GAE). The phytochemical screening of crude methanolic extract of T. recurva possesses phenol, alkaloids, glycosides, saponins, carbohydrates, phytosterols, and tannins. Plant methanolic extract showed very negligible clot lysis (4.21%) and membrane stabilizing property (16.12%) at 10 mg/ml dose. Total phenolic content was found to have 5.89 mg of GAE/gm of extractives. We do believe this plants deserve further research, and wish to endeavor every possible source of new medicine, because, to discover cure to disease no stone should be left unturned.

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