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Abstract

Abstract:
Background: Diabetic nephropathy (DN) is one of the microvascular complications of diabetes and almost the leading cause of end-stage kidney failure in the world, responsible for morbidity and mortality. Currently the management strategy for DN consists of antihypertensive and antiproteinuric measures but these therapies have been suboptimal. Many herbs have been recommended for treating DN as an adjuvant therapy. However, the recommendations are mostly based on animal studies. Thus, the evidences about their mechanisms and clinical usefulness are limited.

Purpose: This review focused on the medicinal herbs which can treat DN.

Method: The search was done in PubMed, Science Direct, Scopus, Web of Science and Google Scholar databases a 15-year period between 2004 to 2019 with keywords search of medicinal plant, plant extract, diabetic nephropathy, Traditional Chinese medicine.

Results: According to the results, many plants showed positive effects but Astragalus polysaccharides, Panax Notoginoside, Berberine had the best DN treatment effects with exact mechanisms of action.
Conclusion: It seems that using these medicinal plants or the extraction of their active ingredients as complementary therapeutics will improve the management of DN in patients.

How to Cite

HEI, W. (2019). Review of Traditional Chinese Medicine for treating Diabetic Nephropathy. Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology, 6(4). https://doi.org/10.15562/phytomedicine.2019.108

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