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Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their antioxidative activity

Abstract

Searching for bioactive agents from medicinal plants, the phytochemical investigation on the EtOAc extract of the Vietnamese Styrax argentifolius leaves has resulted in the isolation and structural determination of five compounds, including one nor-neolignan egonoic acid (1), one lignan (+)-pinoresinol (2), one sterol (20R)-3β-hydroxysitgmasta-5,22-dien-7-one (3), and two triterpenoids lupeol (4), and 2α,3α,24-trihydroxy-urs-12-en-28-oic acid (5). The chemical structures of these secondary metabolites were elucidated by NMR and MS spectral data. All isolated compounds were first observed in S. argentifolius species. Sterol 3 and triterpenoid 5 were detected in genus Styrax for the first time. With the IC50 value of 19.10 µg/mL, compound 2 possessed the strong activity in DPPH radical scavenging assay.

How to Cite

Nguyen Thanh, T., Pham Van, C., Nguyen Thi Thu, H., Le, T. A., & Ninh The, S. (2021). Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their antioxidative activity. Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology, 8(2). https://doi.org/10.15562/phytomedicine.2021.160

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