ORIGINAL ARTICLE

Elucidation of membrane stabilizing Potentials of Methanolic Extract of Vigna unguiculata (cowpea) Linn (seed)

Md. Saddam Hussain , Mohammad Salim Hossain, Niloy Sen, Md. Abdur Rahman, Md. Abdul Halim

Md. Saddam Hussain
Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh. Email: shussain070591@gmail.com

Mohammad Salim Hossain
Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh

Niloy Sen
Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh

Md. Abdur Rahman
Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh

Md. Abdul Halim
Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
Online First: January 15, 2017 | Cite this Article
Hussain, M., Hossain, M., Sen, N., Rahman, M., Halim, M. 2017. Elucidation of membrane stabilizing Potentials of Methanolic Extract of Vigna unguiculata (cowpea) Linn (seed). Discovery Phytomedicine 4(1): 8-12. DOI:10.15562/phytomedicine.2017.35


Different concentration of methanolic extracts of seeds of Vigna unguiculata (cowpea) Linn collected from the local area of Noakhali, Bangladesh were studied for membrane Stabilizing Assay. V.unguiculata Linn seeds were initially collected, processed and extracted with methanol. Then, five different concentration (1mg/ml, 3mg/ml, 5mg/ml, 7mg/ml, 9mg/ml) of methanolic extract of Cowpea (V.unguiculata) were subjected for determination of membrane stabilizing activity. In the assay for membrane stabilizing activity, five different concentration of crude methanol extract capable to inhibit hemolysis of erythrocyte membrane dose dependently in hypotonic solution and heat- induced conditions, which indicates the anti-inflammatory property of the samples. Where, Acetyl salicylic acid was used as standard drug. From the above discussion it is clear that Vigna unguiculata Linn seeds methanolic extract showed significant anti-inflammatory potentials. So, it will be very much possible source for isolating lead compound for curing inflammatory disorder.
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