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Elucidation of membrane stabilizing Potentials of Methanolic Extract of Vigna unguiculata (cowpea) Linn (seed)

Abstract

Different concentration of methanolic extracts of seeds of Vigna unguiculata (cowpea) Linn collected from the local area of Noakhali, Bangladesh were studied for membrane Stabilizing Assay. V.unguiculata Linn seeds were initially collected, processed and extracted with methanol. Then, five different concentration (1mg/ml, 3mg/ml, 5mg/ml, 7mg/ml, 9mg/ml) of methanolic extract of Cowpea (V.unguiculata) were subjected for determination of membrane stabilizing activity. In the assay for membrane stabilizing activity, five different concentration of crude methanol extract capable to inhibit hemolysis of erythrocyte membrane dose dependently in hypotonic solution and heat- induced conditions, which indicates the anti-inflammatory property of the samples. Where, Acetyl salicylic acid was used as standard drug. From the above discussion it is clear that Vigna unguiculata Linn seeds methanolic extract showed significant anti-inflammatory potentials. So, it will be very much possible source for isolating lead compound for curing inflammatory disorder.

How to Cite

Hussain, M. S., Hossain, M. S., Sen, N., Rahman, M. A., & Halim, M. A. (2017). Elucidation of membrane stabilizing Potentials of Methanolic Extract of Vigna unguiculata (cowpea) Linn (seed). Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology, 4(1), 8–12. https://doi.org/10.15562/phytomedicine.2017.35

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