ORIGINAL ARTICLE

Thrombolytic activity of Lagerstroemia speciosa Leaves

Md.Arifur Rahman Chowdhury , Md.Rasadul Islam, Md.Ataul Gani Muktadir

Md.Arifur Rahman Chowdhury
Department of Pharmacy State University of Bangladesh & Department of Pharmacy Southeast University,Bangladesh. Email: arifur.mpharm@gmail.com

Md.Rasadul Islam
Department of Pharmacy State University of Bangladesh & Department of Pharmacy Southeast University, Bangladesh

Md.Ataul Gani Muktadir
Department of Pharmacy State University of Bangladesh & Department of Pharmacy Southeast University, Bangladesh
Online First: October 15, 2017 | Cite this Article
Chowdhury, M., Islam, M., Gani Muktadir, M. 2017. Thrombolytic activity of Lagerstroemia speciosa Leaves. Discovery Phytomedicine 4(4): 41-45. DOI:10.15562/phytomedicine.2017.48


Aim: to investigate the thrombolytic activity of Lagerstroemia speciosa leaf extract.
Methods: thrombolytic activity assayed by an in vitro thrombolytic activity model performed on 10 apparently healthy subjects (both male and female), where the clot lysis ability of methanolic extract of Lagerstroemia speciosa leaves compared with Streptokinase a positive control and saline water as a negative control.
Result: Fraction of methanolic extract of Lagerstroemia speciosa exhibited significant percentage (%) of clot lysis of 25.42% compared to positive control streptokinase of 31.06% loss of clot while the negative control water revealed 3.81% loss of the clots.
Conclusion: The present investigation revealed that the methanol extracts of the leaves of Lagerstroemia speciosa possess potent thrombolytic properties may refer to the treatment of cardiovascular diseases.
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