ORIGINAL ARTICLE

The proliferation and differentiation of pre-osteoblastic MC3T3-E1 cells from Vietnamese drug formulations

Son Ninh The , Hang Pham Thi Thuy, Viet Chu Thi Bich

Son Ninh The
. Email: yamantson@gmail.com

Hang Pham Thi Thuy


Viet Chu Thi Bich

Online First: October 15, 2019 | Cite this Article
Ninh The, S., Pham Thi Thuy, H., Chu Thi Bich, V. 2019. The proliferation and differentiation of pre-osteoblastic MC3T3-E1 cells from Vietnamese drug formulations. Discovery Phytomedicine 6(4). DOI:10.15562/phytomedicine.2019.96


A public heath problem, osteoporosis, is recognized as the prevalent disease, and mainly causes for impairment and loss mass of bone. It closely related the balance between bone formation by osteoblasts and resorption by osteoclasts during the remodeling cycle of bone. Hence, pharmaceutical therapies are looking for the potential agents to stimulate osteoblastic bone formation, as well as inhibit osteoclastic processes.

References

Kumagai M, Mishima T, Wanatabe A, Harada T, Yoshida I, Fujita K, Watai M, Tawata S, Nishikawa K, Morimoto Y, 5,6-Dehydrokawain from Alpinia zerumbet promotes osteoblastic MC3T3-E1 cell differentiation. Biosci Biotechnol Biochem. 2016; 80:1425–1432 https://doi.org/10.1080/09168451.2016.1153959.

Thu HE, Mohamed IN, Hussain Z, Mohamed N, Shuid AN, Eurycoma longifolia, a Malaysian medicinal herb, significantly upregulates proliferation and differentiation in pre-osteoblasts (MC3T3-E1): An in vitro model. Int J Pharm Pharm Sci. 2016;8:199–204 https://doi.org/10.22159/ijpps.2016v8i11.14518.

Son NT, A review on the medicinal plant Dalbergia odorifera species: Phytochemistry and biological activity. Evid Based Complement Alternat Med. 2017;2017:ID 7142370 https://doi.org/10.1155/2017/7142370.

Tai BH, Cuong NM, Huong TT, Choi EM, Kim JA, Kim YH. Chrysoeriol isolated from the leaves of Eurya ciliata stimulates proliferation and differentiation of osteoblastic MC3T3-E1 cells. J Asian Nat Prod Res. 2009;11:817–823 https://doi.org/10.1080/10286020903117317.

Tai BH, Huyen VT, Huong TT, Nhiem NX, Choi EM, Kim JA, Long PQ, Cuong NM, Kim YH. New pyrano-pyrone from Goniolamus tamirensis enhances the proliferation and differentiation of obsteoblastic MC3T3-E1 cells. Chem Pharm Bull. 2010;58:521–525 https://doi.org/10.1248/cpb.58.521.

Lee YK, Song J, Lee SB, Kim KM, Choi SH, Kim CK, Legeros RZ, Kim KN. Proliferation, differentiation, calcification of preosteoblast-like MC3T3-E1 cells cultured onto noncrystaline calcium phosphate glass. J. Biomed Mater Res A 2004;69:188-195 https://doi.org/10.1002/jbm.a.20137.


No Supplementary Material available for this article.
Article Views      : 0
PDF Downloads : 0