Free radical, oxidative stress and diabetes mellitus: A mini review

Md. Saiful Islam Arman

Md. Saiful Islam Arman
International Islamic University Chittagong Kumira, Chittagong-4318, Bangladesh. Email:
Online First: July 15, 2019 | Cite this Article
Arman, M. 2019. Free radical, oxidative stress and diabetes mellitus: A mini review. Discovery Phytomedicine 6(3). DOI:10.15562/phytomedicine.2019.98

According to both experimental and clinical studies it is proposed that oxidative stress play a vital role in the development of type 1and type 2 Diabetes. Human body is affected with diabetic mellitus through destruction of beta cell that may be the outcome of oxidative stress. Oxidative stress a familiar term that may be coined as the imbalance between level of free radical and antioxidant. As free radicals are highly reactive, the pathologic phenomenon of reactive oxygen species (ROS) and reactive nitrogen species (RNS) is to interrupt the function of lipid, protein and DNA. Increased level of oxidative stress in our body tissue and blood is considered to play a critical role in diabetes mellitus. The goal of this review is to concise the how the free radicals propagate in our body and gradually causes diabetes mellitus.

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